Effects of comorbidity burden and age on brain integrity in HIV

TitleEffects of comorbidity burden and age on brain integrity in HIV
Publication TypeJournal Article
Year of Publication2019
AuthorsSaloner, R, Heaton, RK, Campbell, LM, Chen, A, Franklin, Jr., D, Ellis, RJ, Collier, AC, Marra, C, Clifford, DB, Gelman, B, Sacktor, N, Morgello, S, J McCutchan, A, Letendre, S, Grant, I, Fennema-Notestine, C, CHARTER Study Group
JournalAIDS
Volume33
Start Page1175
Issue7
Date Published06/2019
KeywordsAging, Brain, Comorbidity, HIV, Magnetic Resonance Spectroscopy, MRI, neurocognitive disorders
Abstract

The influence of confounding neurocognitive comorbidities in people living with HIV (PLWH) on neuroimaging has not been systematically evaluated. We determined associations between comorbidity burden and brain integrity and examined the moderating effect of age on these relationships.
 

DOI10.1097/QAD.0000000000002192