AIDS myelopathy is not associated with elevated HIV viral load in cerebrospinal fluid

Date Published:
08/2000

Publication Type:
Journal Article

Authors:

Secondary:
Neurology

Volume:
55

Pagination:
440-442

Issue:
3

URL:
https://pubmed.ncbi.nlm.nih.gov/

Keywords:
Internal;RNA;Spinal Cord Diseases;Viral

Abstract:
<p>The pathogenesis of AIDS-associated myelopathy is unknown. Elevated HIV-1 viral load in CSF has been associated with cognitive impairment. The authors investigated if a similar association exists in patients with myelopathy. The authors evaluated levels of HIV-1 RNA in the CSF of 16 individuals with AIDS myelopathy and in 16 nonmyelopathic HIV-infected control subjects. There was no correlation between levels of HIV-1 RNA and the presence or severity of myelopathy.</p>