Date Published:
12/2009

Publication Type:
Journal Article

Authors:

M. Lechowicz
D.P. Dittmer
J.Y. Lee
S.E. Krown
W. Wachsman
D. Aboulafia
B.J. Dezube
L. Ratner
J.W. Said
R.F. Ambinder

Secondary:
Clinical Infectious Diseases: An Official Publication of the Infectious Diseases Society of America

Volume:
49

Pagination:
1946-1949

Issue:
12

URL:
https://pubmed.ncbi.nlm.nih.gov/

DOI:
10.1086/648447

Keywords:
Acquired Immunodeficiency Syndrome;Adult;External;Female;Herpesvirus 8;Human;Humans;Kaposi;Male;Middle Aged;Prospective Studies;RNA;Sarcoma;Valproic Acid;Viral

Abstract:
<p>The AIDS Malignancy Consortium undertook a pilot trial of valproic acid among patients with AIDS-associated Kaposi sarcoma (KS). Treatment was associated with low toxicity, but the KS clinical response and KS herpesvirus lytic induction rates were not sufficiently high to meet predefined criteria for efficacy.</p>