A case of primary HIV type 1 and cytomegalovirus coinfection presenting with widespread clinical disease.

Date Published:
2014 May-Jun

Publication Type:
Journal Article

Authors:

Secondary:
J Int Assoc Provid AIDS Care

Volume:
13

Pagination:
196-9

Issue:
3

PMID:
24476962

URL:
https://pubmed.ncbi.nlm.nih.gov/24476962

DOI:
10.1177/2325957413519289

Keywords:
Adult;Alanine Transaminase;Anti-Retroviral Agents;Aspartate Aminotransferases;Coinfection;Cytomegalovirus Infections;Drug Therapy, Combination;External;Fever;Fundus Oculi;Hepatitis B Antibodies;HIV Infections;HIV-1;Humans;Hypesthesia;Male;Meningitis, Viral;Paresthesia;Retinal Diseases

Abstract:
<p>Coinfection of HIV-1 and cytomegalovirus (CMV) may occur given the shared routes of transmission, and the clinical presentations of each process overlap. We present a case of acute HIV-1 and CMV coinfection presenting with an acute febrile illness complicated by meningitis, hepatitis, and retinopathy. This and other similar cases demonstrate the need to consider CMV coinfection in acute HIV-1 disease, particularly in situations with significant end-organ damage.</p>