Stability of human immunodeficiency virus type 1 RNA in cerebrospinal fluid determined with the AMPLICOR HIV-1 MONITOR test, version 1.5 (ultrasensitive)

TitleStability of human immunodeficiency virus type 1 RNA in cerebrospinal fluid determined with the AMPLICOR HIV-1 MONITOR test, version 1.5 (ultrasensitive)
Publication TypeJournal Article
Year of Publication2002
AuthorsSinger, EJ, Aronow, HA, Lee, SY, Hinkin, CH, Lazarus, T
JournalJournal of Clinical Microbiology
Volume40
Issue10
Pagination3863-4
Date Published10/2002
KeywordsDiagnostic, Internal, Reagent Kits, RNA, RNA Stability, Viral
Abstract

We evaluated the effects of time, temperature, freezing, and thawing on the cerebrospinal fluid viral load by using the Roche AMPLICOR HIV-1 MONITOR test, version 1.5 (ultrasensitive). While a statistically significant decrease from the baseline was observed at 24 h, but not at 6 or 12 h, and with one freeze-thaw cycle, all changes were within the range of intra-assay variability.

URLhttp://www.ncbi.nlm.nih.gov/pubmed/12354902