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HIV-associated dementia, Alzheimer's disease, multiple sclerosis, and schizophrenia: gene expression review

Submitted by dcc on Wed, 04/23/2014 - 7:47am
TitleHIV-associated dementia, Alzheimer's disease, multiple sclerosis, and schizophrenia: gene expression review
Publication TypeJournal Article
Year of Publication2004
AuthorsMinagar, A, Shapshak, P, Duran, EM, Kablinger, AS, Alexander, JS, Kelley, RE, Seth, R, Kazic, T
JournalJournal of the Neurological Sciences
Volume224
Issue1-2
Pagination3-17
Date Published09/2004
KeywordsAlzheimer Disease, External, Schizophrenia
Abstract

RNA and protein gene expression technologies are revolutionizing our view and understanding of human diseases and enable us to analyze the concurrent expression patterns of large numbers of genes. These new technologies allow simultaneous study of thousands of genes and their changes in regulation and modulation patterns in relation to disease state, time, and tissue specificity. This review summarizes the application of this modern technology to four common neurological and psychiatric disorders: HIV-1-associated dementia, Alzheimer's disease, multiple sclerosis, and schizophrenia and is a first comparison of these diseases using this approach.
URLhttp://www.ncbi.nlm.nih.gov/pubmed/15450765