Global NeuroAIDS roundtable.
Title | Global NeuroAIDS roundtable. |
Publication Type | Journal Article |
Year of Publication | 2013 |
Authors | Joseph, J, Achim, C, Boivin, MJ, Brew, BJ, Clifford, DB, Colosi, DA, Ellis, RJ, Heaton, RK, Gallo-Diop, A, Grant, I, Kanmogne, GD, Kumar, M, Letendre, S, Marcotte, TD, Nath, A, Pardo, C, Paul, RH, Pulliam, L, Robertson, K, Royal, W, Sacktor, N, Sithinamsuwan, P, Smith, DM, Valcour, V, Wigdahl, B, Wood, C |
Journal | J Neurovirol |
Volume | 19 |
Issue | 1 |
Pagination | 1-9 |
Date Published | 2013 Feb |
ISSN | 1538-2443 |
Keywords | AIDS Dementia Complex, Global Health, Health Services Needs and Demand, Humans, Neuropsychological Tests |
Abstract | In May 2012, the Division of AIDS Research at the National Institute of Mental Health (NIMH) organized the "Global NeuroAIDS Roundtable" in conjunction with the 11th International Symposium on Neurovirology and the 2012 Conference on HIV in the Nervous System. The meeting was held in New York, NY, USA and brought together NIMH-funded investigators who are currently working on projects related to the neurological complications of AIDS (NeuroAIDS) in Africa, Asia, Eastern Europe, and Latin America in order to provide an opportunity to share their recent findings and discuss the challenges encountered within each country. The major goals of the roundtable were to evaluate HIV-associated neurocognitive impairment and determine if it may be directly attributable to distinct HIV subtypes or clades and to discuss the future priorities for global NeuroAIDS research. At the "Global NeuroAIDS Roundtable", presentations of preliminary research indicated that HIV-associated neurocognitive impairment is prevalent in all countries examined regardless of which HIV clade is present in the region. The only clear-cut difference between HIV-1 clades was in relation to subtypes A and D in Uganda. However, a key point that emerged from the discussions was that there is an urgent need to standardize neurocognitive assessment methodologies across the globe before definitive conclusions can be drawn regarding the relationship between HIV clade diversity and neuropathogenesis. Future research directions were also discussed at the roundtable with particular emphasis on the potential of viral and host factor molecular interactions to impact the pathophysiology of HIV-associated neurocognitive disorders (HAND) from a global perspective. |
DOI | 10.1007/s13365-012-0143-9 |
Alternate Journal | J. Neurovirol. |
PubMed ID | 23354550 |
PubMed Central ID | PMC3713197 |
Grant List | MH073433 / MH / NIMH NIH HHS / United States MH076651 / MH / NIMH NIH HHS / United States MH077487 / MH / NIMH NIH HHS / United States MH078748 / MH / NIMH NIH HHS / United States MH080611 / MH / NIMH NIH HHS / United States MH080612 / MH / NIMH NIH HHS / United States MH083465 / MH / NIMH NIH HHS / United States MH083489 / MH / NIMH NIH HHS / United States MH083573 / MH / NIMH NIH HHS / United States MH085604 / MH / NIMH NIH HHS / United States MH086356 / MH / NIMH NIH HHS / United States MH092225 / MH / NIMH NIH HHS / United States MH094159 / MH / NIMH NIH HHS / United States MH094160 / MH / NIMH NIH HHS / United States NS055628 / NS / NINDS NIH HHS / United States NS055653 / NS / NINDS NIH HHS / United States P30 MH062512 / MH / NIMH NIH HHS / United States R01 CA075903 / CA / NCI NIH HHS / United States R01 DA019807 / DA / NIDA NIH HHS / United States R01 MH086356 / MH / NIMH NIH HHS / United States R01 NS074903 / NS / NINDS NIH HHS / United States U01 MH083506 / MH / NIMH NIH HHS / United States U24 MH100928 / MH / NIMH NIH HHS / United States |