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Elevated substance P levels in HIV-infected women in comparison to HIV-negative women

Submitted by dcc on Wed, 04/23/2014 - 7:47am
TitleElevated substance P levels in HIV-infected women in comparison to HIV-negative women
Publication TypeJournal Article
Year of Publication2008
AuthorsDouglas, SD, Cnaan, A, Lynch, KG, Benton, T, Zhao, H, Gettes, DR, Evans, DL
JournalAIDS Research and Human Retroviruses
Volume24
Pagination375-8
Date Published2008
KeywordsAdolescent, Adult, Aged, External, Female, HIV Infections, Humans, Middle Aged, Substance P
Abstract

Substance P and its receptor (neurokinin-1R) are potent modulators of neuroimmunoregulation and HIV/AIDS infection. We previously demonstrated that HIV-seropositive men had significantly higher substance P levels compared to uninfected controls. We now demonstrate that substance P plasma levels are significantly higher in HIV-infected women in comparison to uninfected control women.
URLhttp://www.ncbi.nlm.nih.gov/pubmed/18327973