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AIDS myelopathy is not associated with elevated HIV viral load in cerebrospinal fluid

Submitted by dcc on Wed, 04/23/2014 - 7:47am
TitleAIDS myelopathy is not associated with elevated HIV viral load in cerebrospinal fluid
Publication TypeJournal Article
Year of Publication2000
AuthorsGeraci, A, DiRocco, A, Liu, M, Werner, P, Tagliati, M, Godbold, J, Simpson, DM, Morgello, S
JournalNeurology
Volume55
Issue3
Pagination440-442
Date Published08/2000
KeywordsInternal, RNA, Spinal Cord Diseases, Viral
Abstract

The pathogenesis of AIDS-associated myelopathy is unknown. Elevated HIV-1 viral load in CSF has been associated with cognitive impairment. The authors investigated if a similar association exists in patients with myelopathy. The authors evaluated levels of HIV-1 RNA in the CSF of 16 individuals with AIDS myelopathy and in 16 nonmyelopathic HIV-infected control subjects. There was no correlation between levels of HIV-1 RNA and the presence or severity of myelopathy.
URLhttp://www.ncbi.nlm.nih.gov/pubmed/10932285